Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Oct 26;9:6609–6618. doi: 10.2147/OTT.S107101

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 Jiang et al. This work is published and licensed by Dove Medical Press Limited

The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

SIL induced the autophagy of the ACC-M cells.

Notes: (A) AVs detection by MDC staining (fluorescence microscope, ×200). (a1) The control group; (a2) the SIL-treatment groups, 80 µg/mL. (B) Ultrastructures of AVs by TEM. (b1) The control group: clear nucleoli, large nuclear/cytoplasm ratio, aside-shifted nucleoli, even cytoplasm matrix density (×5,000); (b2) AVs in the cells of the SIL-treatment group (×5,000). (C) Expression detection of LC3-I and LC3-II by Western blot. (c1) Expressions after cultured with different concentrations of SIL for 24 hours; (c2) expressions of LC3-I and LC3-II after 100 µg/mL of SIL acted on the ACC-M cells at different time periods.

Abbreviations: ACC-M, human lung high metastasis cell line of salivary gland adenoid cystic carcinoma; AVs, autophagic vacuoles; LC3, light-chain 3; MDC, monodansyl cadaverine; SIL, silibinin; TEM, transmission electron microscopy.