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. 2016 Oct 1;9(10):1203–1210. doi: 10.1242/dmm.024406

Fig. 5.

Fig. 5.

Ribavirin treatment of LA-B350-infected rats delays virus shedding and significantly reduces viral loads in the liver. Twelve rats were infected intravenously with rat HEV LA-B350. Afterwards, six of these rats were injected daily with ribavirin at 30 mg/kg body weight (red), whereas the other six were injected with PBS (black), for 14 days. Rat HEV was quantified in feces (A) and in liver 21 days after infection (B). Values represent individual values for each rat; significance was calculated through the Mann–Whitney U-test (B). LOD, limit of detection.