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. 2016 Oct 27;57(11):1976–1986. doi: 10.1194/jlr.R066597

Fig. 4.

Fig. 4.

Protein carbonylation and formation of protein-lipid adducts. Alkylation of the side chains of lysine, histidine, and cysteine are shown and the major affected mitochondrial pathways. For diagrammatic purposes, only the modification of amino acid side chains by 4-HNE is shown. Additional parallel modification reactions with other electrophiles occur.