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. 2016 Oct 31;11(10):e0164898. doi: 10.1371/journal.pone.0164898

Table 3. Meta-analysis results for models 1 to 3 from the linear mixed model for the log odds ratio of surviving under experimental treatment compared to the control treatment using data for 17 trials [42].

Model 1 Model 2 Model 3
Covariance structures Between random time effects (Σ) Indepa CSb HAR(1)c
Within-study errors (Si) Indep Indep Indep
Log odds ratio estimates
Month 6 0.22 (0.02, 0.43) 0.22 (-0.01, 0.45) 0.22 (0.02, 0.43)
Month 12 0.39 (0.22, 0.57) 0.41 (0.21, 0.61) 0.39 (0.21, 0.57)
Month 18 0.49 (0.27, 0.71) 0.50 (0.25, 0.74) 0.47 (0.21, 0.72)
Month 24 0.40 (0.04, 0.76) 0.38 (0.12, 0.65) 0.42 (0.05, 0.78)
Between study variance estimates
Month 6 0.00 τ2 = 0.03 0.00
Month 12 0.00 0.01
Month 18 0.00 0.05
Month 24 0.20 0.23
Model Fit
AICd 121.3 119.6 120.5

aIndep = Independence

bCS = Compound Symmetry

cHAR(1) = Heteroscedastic autoregressive (1)

dAIC = Akaike Information Criterion