Table 1. Enriched signaling pathways in upregulated and downregulated genes in PTE pulmonary artery.
| Regulation | KEGG ID | Description | Gene count | P value |
|---|---|---|---|---|
| Up-regulated | 4660 | T cell receptor signaling pathway | 23 | 4.0E-04 |
| Up-regulated | 4621 | NOD-like receptor signaling pathway | 13 | 1.6E-03 |
| Up-regulated | 4622 | RIG-I-like receptor signaling pathway | 13 | 3.0E-03 |
| Up-regulated | 4062 | Chemokine signaling pathway | 25 | 4.0E-03 |
| Up-regulated | 4664 | Fc epsilon RI signaling pathway | 14 | 6.8E-03 |
| Up-regulated | 4620 | Toll-like receptor signaling pathway | 14 | 2.2E-02 |
| Up-regulated | 4662 | B cell receptor signaling pathway | 13 | 2.6E-02 |
| Down-regulated | 4020 | Calcium signaling pathway | 19 | 2.1E-02 |