Table 1.

Periostin Expression Levels and Clinicopathologic Features of 149 Hepatocellular Carcinoma Cases

Clinicopathologic data	No. of cases	Periostin expression		p-value
		Low	High
Age, yr				0.945
≤56	75	44	31
>56	74	43	31
Sex				0.146
Male	111	61	50
Female	38	26	12
Etiology				0.690
HBV	115	69	46
HCV	13	6	7
Alcohol	18	10	8
Cryptogenic	3	2	1
Child-Pugh class				1.000*
A	147	61	86
B	2	1	1
Tumor size, cm				0.236
≤5	104	64	40
>5	45	23	22
Tumor no.				0.013†
Single	120	76	44
Multiple	29	11	18
Microvascular invasion				0.003†
Yes	43	17	26
No	106	70	36
Edmondson grade				0.560
I–II	93	56	37
III–IV	56	31	25
Serum α-fetoprotein, ng/mL				0.578
≤200	102	58	44
>200	47	29	18
Modified UICC stage				0.003†
I–II	110	72	38
III–IV	39	15	24
Tumor capsule				0.806
Yes	92	53	39
No	57	34	23

HBV, hepatitis B virus; HCV, hepatitis C virus; UICC, Union for International Cancer Control.

^*Fischer exact test;

^†p<0.05.