Table 1.
Indications for Antiviral Treatment Used in This Study
| Korean NHI | EASL | New extended indication | |
|---|---|---|---|
| Liver enzyme | AST or ALT ≥80 IU/L | ALT ≥ULN*×1 | Any |
| HBV DNA level, IU/mL | ≥20,000† | ≥2,000 | ≥2,000 |
NHI, National Health Insurance; EASL, European Association for the Study of the Liver; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ULN, upper limit of normal; HBV, hepatitis B virus.
*
ULN was defined as 33 IU/L in men and 25 IU/L in women;17
†
≥2,000 IU/mL in case of hepatitis B e antigen (−) chronic hepatitis B or liver cirrhosis.