Table 3.
Creatinine-adjusted NNK metabolite levels (pmol/mg creatinine) in the urine of smokers (n=180).a
NNAL-N-Gluc | (R)-NNAL-O-Gluc | (S)-NNAL-O-Gluc | Total NNAL-Gluc | Free NNAL | Total NNAL | |
---|---|---|---|---|---|---|
Mean | 0.62 ± 0.49 | 0.59 ± 0.44 | 0.72 ± 0.50 | 1.93 ± 1.23 | 0.78 ± 0.60 | 2.71 ± 1.61 |
Range | 0.06 - 3.23b | 0.10 - 2.78c | 0.06 - 2.96d | 0.14 - 6.31 | 0.11- 3.29e | 0.26 - 9.45 |
All concentrations listed are in pmol/mg creatinine (mean ± SD) for 180 metabolite-informative subjects.
n=161; 19 subjects were below the detection limit for NNAL-N-Gluc;
n=171; 9 subjects were below the detection limit for (R)-NNAL-O-Gluc;
n=178; 2 subjects were below the detection limit for (S)-NNAL-O-Gluc;
n=167; 13 subjects were below the detection limit for free NNAL.