Table 1.
UPLC conditions for detection of phase I exemestane metabolites.
Time (min) | % Aa | % B | % C | curve |
---|---|---|---|---|
initial | 70 | 20 | 10 | initial |
0.5 | 70 | 20 | 10 | 11 |
9 | 30 | 60 | 10 | 6 |
9.5 | 0 | 90 | 10 | 6 |
10 | 70 | 20 | 10 | 6 |
Mobile phase A, 0.1% formic acid; mobile phase B, 100% methanol; mobile phase C, 100% acetonitrile. Flow rate = 0.4 mL/min.