Table 2.
Neuropsychological Test | Total cholesterol2 × Age | LDL cholesterol2 × Age | ||||||
---|---|---|---|---|---|---|---|---|
b | SE | p | r2 † | b | SE | p | r2 † | |
Digit Span Forward (total score) | −.00002 | .0002 | .90 | .0001 | .00001 | .0002 | .96 | <.0001 |
Digit Span Backward (total score) | −.0004 | .0002 | .057 | .0192 | −.0005 | .0003 | .057 | .0194 |
Logical Memory I (total score) | −.0005 | .0005 | .31 | .0051 | −.0005 | .0007 | .50 | .0023 |
Logical Memory II (total score) | −.0013 | .0006 | .039 | .0202 | −.0012 | .0008 | .14 | .0106 |
Visual Reproduction I (log total score) | −.00001 | .00001 | .61 | .0013 | −.00002 | .00002 | .27 | .0062 |
Visual Reproduction II (total score) | −.0009 | .0007 | .21 | .0075 | −.0020 | .0009 | .026 | .0236 |
Trail Making Test, Part A (log seconds) | .00001 | .00003 | .62 | .0013 | .00004 | .00004 | .22 | .0080 |
Trail Making Test, Part B (log seconds) | .00004 | .00003 | .19 | .0081 | .0001 | .00004 | .044 | .0195 |
Judgment of Line Orientation (total score) | −.0002 | .0003 | .50 | .0019 | −.0004 | .0004 | .32 | .0041 |
Block Design (total score) | −.0009 | .0007 | .19 | .0078 | −.0017 | .0009 | .059 | .0158 |
Grooved Pegboard Test, dominant (log seconds) | .00002 | .00001 | .14 | .0091 | .00002 | .00002 | .16 | .0083 |
Grooved Pegboard Test, non-dominant (log seconds) | .00003 | .00002 | .073 | .0152 | .00004 | .00002 | .068 | .0157 |
Models adjusted for age, sex, education, systolic blood pressure, glucose, smoking, alcohol use, depressive symptoms, antihypertensive medication use, and lipid-lowering medication use. Total and LDL cholesterol examined in separate models. Only quadratic cholesterol terms are presented here for brevity; all models included linear cholesterol terms and were fully specified (i.e., cholesterol, cholesterol × age, cholesterol2, cholesterol2 × age).
Values represent covariate-adjusted squared semi-partial correlation coefficients.
Abbreviation: LDL = low-density lipoprotein