Table 3.
Mean values of measured parameters during baseline and subsequent 20 s periods following i.v. adenosine (512 μg) and placebo bolus injections
| Measured parameter | Baseline values | 20 s after bolus injection | Between 20 and 40 s | Between 40 and 60 s |
|---|---|---|---|---|
| Adenosine (n = 24) | ||||
| VI (l min−1) | 7.6 ± 0.5 | 7.5 ± 0.5 | 7.5 ± 0.5 | 7.7 ± 0.4 |
| VT (l) | 0.58 ± 0.03 | 0.56 ± 0.03 | 0.57 ± 0.03 | 0.57 ± 0.03 |
| BR (breaths min−1) | 13.3 ± 0.7 | 13.5 ± 0.8 | 13.5 ± 0.7 | 13.7 ± 0.7 |
| HR (beats min–1) | 64.8 ± 0.8 | 64 ± 0.8 | 64.1 ± 0.8 | 63.8 ± 0.8 |
| SBP (mmHg) | 144.9 ± 3.4 | 144.8 ± 3.2 | 145.6 ± 3.3 | 145.4 ± 3.6 |
| DBP (mmHg) | 83.1 ± 3 | 82.8 ± 2.9 | 83.1 ± 3 | 83.1 ± 3.1 |
| MAP (mmHg) | 105.7 ± 3.4 | 105.3 ± 3.2 | 105.7 ± 3.3 | 105.8 ± 3.5 |
| Placebo (n = 18) | ||||
| VI (l min−1) | 8.4 ± 0.5 | 8.2 ± 0.4 | 8.2 ± 0.5 | 8.1 ± 0.5 |
| VT (l) | 0.66 ± 0.05 | 0.63 ± 0.05 | 0.62 ± 0.05 | 0.65 ± 0.06 |
| BR (breaths min−1) | 13.5 ± 0.7 | 13.6 ± 0.8 | 13.7 ± 0.8 | 13.4 ± 0.9 |
| HR (beats min–1) | 65 ± 1.3 | 64.2 ± 1.2 | 64.5 ± 1.1 | 64.9 ± 1.1 |
| SBP (mmHg) | 145.6 ± 4.6 | 145.8 ± 4.6 | 146.9 ± 4.5 | 147.4 ± 4.9 |
| DBP (mmHg) | 84.2 ± 3.9 | 84.3 ± 3.8 | 85 ± 3.8 | 85 ± 4 |
| MAP (mmHg) | 106.4 ± 4.4 | 106.3 ± 4.4 | 107.4 ± 4.3 | 107.8 ± 4.6 |
Data are presented as the mean ± SEM.
All P > 0.05 vs. baseline.