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. 2016 Oct 17;594(21):6395–6405. doi: 10.1113/JP272907

Figure 3. Reduced muscle Mn2+ concentration upon inhibition of Nox2 ROS .

Figure 3

The concentration of Mn2+ increased 30 min postinfusion in both the lower leg and the kidney. The mdx mice showed greater Mn2+ accumulation than WT, whereas p47−/−/mdx demonstrated a trend to have less Mn2+ accumulation than mdx mice in the lower leg; P ≤ 0.05 # vs. control, + vs. control and 2 days, and * between groups. Data (means ± SEM) are representative of at least three animals.