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. 2016 Oct 1;6(10):2140–2161.

Figure 1.

Figure 1

The brain metastatic PTC. A. Hematoxylin-eosin staining reveals papillary architectures covered by cuboidal to columnar epithelium. Cellular crowding is visible and neoplastic cells demonstrate nuclear clearing and nuclear grooves. B. TTF-1 staining as a marker for thyroid or lung origin exhibits strong nuclear staining. C. Thyroglobulin shows strong cytoplasmic staining. D. Proliferation marker Ki67 is positive in 20% of cells (original magnification, x400).