Figure 4.

Laser confocal imaging of Aβ _1–42 and LRP1 in hippocampus (original magnification ×600): (A) stack imaging of the three; (B) imaging of cell nucleus; (C) LRP1 labeled with green fluorescence; (D) Aβ _1–42 labeled with red fluorescence; (a) in normal control group, plaque deposits of Aβ _1–42 were not found, while LRP1 was expressed mostly around the vascular endothelial cells; (b) in model group, there were dense-core plaques deposited, while less LRP1 was expressed; (c) in EA group, the senile plaques were relatively reduced, and there were only some diffuse plaques, while the expression of LRP1 was more than that of model group.