Table 2.
Differentially downregulated (<0.83-fold) proteins identified by iTRAQ in F2 treated SGC7901 cells.
| Rank # | Accession | Gene symbol (GN) | Definition (description) | Score | Mass | Cov% | Ration | COG function-description |
|---|---|---|---|---|---|---|---|---|
| Down 1 | tr|F5H740 | VDAC3 | Voltage-dependent anion-selective channel protein 3 | 1114 | 39598 | 41.5 | 0.81 | — |
| Down 2 | sp|Q9H845 | ACAD9 | Acyl-CoA dehydrogenase family member 9, mitochondrial | 311 | 81512 | 21.9 | 0.69 | Acyl-CoA dehydrogenases |
| Down 3 | sp|Q969S9-2 | GFM2 | Isoform 2 of ribosome-releasing factor 2, mitochondrial | 153 | 94059 | 5.1 | 0.80 | Translation elongation factors (GTPases) |
| Down 4 | sp|P35908 | KRT2 | Keratin, type II cytoskeletal 2 epidermal | 338 | 76630 | 18.2 | 0.67 | Myosin heavy chain |
| Down 5 | tr|B7Z8A2 | — | cDNA FLJ51671, highly similar to prenylcysteine oxidase (EC 1.8.3.5) | 492 | 63740 | 23.8 | 0.83 | — |
| Down 6 | sp|Q9Y512 | SAMM50 | Sorting and assembly machinery component 50 homolog | 170 | 59339 | 18.6 | 0.76 | Outer membrane protein/protective antigen OMA87 |
| Down 7 | sp|Q6ZNW5 | GDPGP1 | GDP-D-glucose phosphorylase 1 | 118 | 45302 | 8.6 | 0.78 | — |
| Down 8 | sp|P51970 | NDUFA8 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 | 72 | 25720 | 15.1 | 0.68 | — |
| Down 9 | tr|B4DRW0 | — | cDNA FLJ58125, highly similar to copper-transporting ATPase 1 (EC 3.6.3.4) | 102 | 61873 | 6.1 | 0.78 | Cation transport ATPase |
| Down 10 | tr|Q8NBW7 | KDELR1 | ER lumen protein retaining receptor | 51 | 20327 | 12.7 | 0.73 | ER lumen protein retaining receptor |
| Down 11 | tr|B2R6F5 | — | cDNA, FLJ92928, highly similar to Homo sapiens retinitis pigmentosa 2 (X-linked recessive) (RP2), mRNA | 59 | 47451 | 2.3 | 0.82 | — |
| Down 12 | tr|Q2VIN3 | — | RBM1 (fragment) | 1232 | 45756 | 26.8 | 0.81 | RNA-binding proteins (RRM domain) |
| Down 13 | sp|P14174 | — | Macrophage migration inhibitory factor | 608 | 13856 | 17.4 | 0.71 | — |
| Down 14 | tr|B2R6S4 | — | cDNA, FLJ93089, highly similar to Homo sapiens NCK adaptor protein 1 (NCK1), mRNA | 137 | 53755 | 18.3 | 0.83 | — |
| Down 15 | sp|Q16822 | PCK2 | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial | 1795 | 78784 | 41.6 | 0.74 | Phosphoenolpyruvate carboxykinase (GTP) |
| Down 16 | tr|E9PM12 | TCIRG1 | V-type proton ATPase 116 kDa subunit a isoform 3 (fragment) | 63 | 25815 | 13.3 | 0.74 | Archaeal/vacuolar-type H+-ATPase subunit I |
| Down 17 | sp|Q2T9J0-2 | TYSND1 | Isoform 2 of peroxisomal leader peptide-processing protease | 96 | 43618 | 9.8 | 0.67 | — |
| Down 18 | tr|J3KPX7 | PHB2 | Prohibitin-2 | 1543 | 39466 | 51.8 | 0.82 | Membrane protease subunits, stomatin/prohibitin homologs |
| Down 19 | tr|Q8NCF7 | — | cDNA FLJ90278 fis, clone NT2RP1000325, highly similar to phosphate carrier protein, mitochondrial precursor | 517 | 48576 | 26.9 | 0.81 | — |
| Down 20 | tr|B4E0R0 | — | cDNA FLJ54220, highly similar to Long-chain-fatty-acid-CoA ligase 1 (EC 6.2.1.3) | 100 | 88560 | 6.2 | 0.74 | Long-chain acyl-CoA synthetases (AMP-forming) |
| Down 21 | tr|B3KRY3 | — | cDNA FLJ35079 fis, clone PLACE6005283, highly similar to lysosome-associated membrane glycoprotein 1 | 319 | 48851 | 11.1 | 0.79 | — |
| Down 22 | tr|B3KU09 | — | cDNA FLJ39034 fis, clone NT2RP7008085, highly similar to Homo sapiens ring finger protein 123 (RNF123), mRNA | 110 | 166029 | 2.4 | 0.78 | — |
| Down 23 | sp|Q9BVV7 | TIMM21 | Mitochondrial import inner membrane translocase subunit Tim21 | 86 | 35219 | 13.7 | 0.82 | — |
| Down 24 | sp|Q9UMY1 | NOL7 | Nucleolar protein 7 | 148 | 39504 | 12.5 | 0.78 | — |
| Down 25 | sp|Q9UNN8 | PROCR | Endothelial protein C receptor | 103 | 27909 | 15.1 | 0.80 | — |
| Down 26 | sp|Q86SF2 | GALNT7 | N-Acetylgalactosaminyltransferase 7 | 95 | 89410 | 9.9 | 0.81 | — |
| Down 27 | tr|I3L0U2 | PRSS21 | Testisin (fragment) | 115 | 27083 | 14.7 | 0.82 | Secreted trypsin-like serine protease |
| Down 28 | tr|B7ZLP5 | SAFB | SAFB protein | 557 | 121835 | 13 | 0.83 | — |
| Down 29 | tr|F2Z3N7 | TMEM106B | Transmembrane protein 106B | 135 | 12975 | 12.5 | 0.82 | — |
| Down 30 | tr|B7Z361 | — | Reticulon | 166 | 27838 | 12.2 | 0.76 | — |
| Down 31 | tr|H0Y6F2 | PRR5 | Proline-rich protein 5 (fragment) | 57 | 39929 | 2.3 | 0.78 | — |
| Down 32 | sp|Q7Z7E8 | UBE2Q1 | Ubiquitin-conjugating enzyme E2 Q1 | 92 | 54711 | 1.9 | 0.76 | — |
| Down 33 | tr|A8K4K9 | — | cDNA FLJ76169 | 146 | 42007 | 8.8 | 0.83 | — |
| Down 34 | sp|P13645 | KRT10 | Keratin, type I cytoskeletal 10 | 382 | 66321 | 21.6 | 0.55 | — |
| Down 35 | sp|Q8N5K1 | CISD2 | CDGSH iron-sulfur domain-containing protein 2 | 167 | 20364 | 26.7 | 0.81 | — |
| Down 36 | sp|Q8NI27 | THOC2 | THO complex subunit 2 | 282 | 241732 | 8.7 | 0.83 | — |
| Down 37 | tr|B4DEP8 | — | cDNA FLJ56960, highly similar to Homo sapiens phosphatidylinositol 4-kinase type II (PI4KII), mRNA | 127 | 61711 | 9.8 | 0.76 | — |
| Down 38 | sp|Q5BKZ1 | ZNF326 | DBIRD complex subunit ZNF326 | 145 | 78123 | 7.9 | 0.78 | — |
| Down 39 | tr|Q8IW24 | EXOC5 | Exocyst complex component 5 | 108 | 99962 | 9.3 | 0.82 | — |
| Down 40 | tr|B3KMG6 | — | cDNA FLJ10939 fis, clone OVARC1001065, highly similar to Homo sapiens MTERF domain containing 1 (MTERFD1), mRNA | 117 | 43225 | 9.8 | 0.76 | — |
| Down 41 | sp|Q8NBM4-2 | UBAC2 | Isoform 2 of ubiquitin-associated domain-containing protein 2 | 150 | 37306 | 18.1 | 0.83 | — |
| Down 42 | sp|Q8NGA1 | OR1M1 | Olfactory receptor 1M1 | 76 | 39512 | 2.2 | 0.69 | — |
| Down 43 | tr|E9PN17 | ATP5L | ATP synthase subunit g, mitochondrial | 366 | 11489 | 63.2 | 0.82 | — |
| Down 44 | tr|B2R686 | TGOLN2 | Trans-golgi network protein 2, isoform CRA_a | 166 | 61093 | 13 | 0.79 | — |
| Down 45 | tr|B4DIR5 | — | cDNA FLJ56026 | 51 | 143728 | 1.7 | 0.74 | — |
| Down 46 | tr|J3KS15 | ICT1 | Peptidyl-tRNA hydrolase ICT1, mitochondrial (fragment) | 169 | 26740 | 26 | 0.82 | Protein chain release factor B |
| Down 47 | tr|F5H0F9 | ANAPC5 | Anaphase-promoting complex subunit 5 | 72 | 98300 | 7.5 | 0.82 | — |
| Down 48 | tr|C8C504 | HBB | Beta-globin | 1233 | 20056 | 29.9 | 0.21 | — |
| Down 49 | tr|B2R921 | — | cDNA, FLJ94171, highly similar to Homo sapiens solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 (SLC25A15), nuclear gene encoding mitochondrial protein, mRNA | 53 | 39308 | 9 | 0.77 | — |
| Down 50 | sp|Q9Y613 | FHOD1 | FH1/FH2 domain-containing protein 1 | 255 | 141625 | 8.8 | 0.81 | — |
| Down 51 | sp|Q92643 | PIGK | GPI-anchor transamidase | 110 | 51592 | 10.9 | 0.77 | Glycosylphosphatidylinositol transamidase (GPIT), subunit GPI8 |
| Down 52 | tr|A4FTY4 | TXNRD2 | TXNRD2 protein | 331 | 41672 | 24.6 | 0.79 | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes |
| Down 53 | tr|D3DP46 | SPCS3 | Signal peptidase complex subunit 3 homolog (S. cerevisiae), isoform CRA_a | 147 | 24007 | 18.9 | 0.82 | — |
| Down 54 | sp|Q9Y5Q9 | GTF3C3 | General transcription factor 3C polypeptide 3 | 154 | 117216 | 7.8 | 0.79 | — |
| Down 55 | sp|P60468 | SEC61B | Protein transport protein Sec61 subunit beta | 192 | 11546 | 37.5 | 0.72 | — |
| Down 56 | sp|Q5RI15-2 | — | Isoform 2 of cytochrome c oxidase protein 20 homolog | 106 | 17682 | 20 | 0.83 | — |
| Down 57 | sp|Q9P206-2 | — | Isoform 2 of uncharacterized protein KIAA1522 | 146 | 128602 | 6.5 | 0.73 | — |
| Down 58 | sp|Q86YN1 | DOLPP1 | Dolichyldiphosphatase 1 | 64 | 28953 | 5.5 | 0.69 | Membrane-associated phospholipid phosphatase |
| Down 59 | sp|O00165-2 | — | Isoform 2 of HCLS1-associated protein X-1 | 111 | 34281 | 16 | 0.81 | — |
| Down 60 | tr|B4E303 | — | cDNA FLJ57449, highly similar to Notchless homolog 1 | 127 | 54134 | 16.5 | 0.82 | FOG: WD40 repeat |
| Down 61 | sp|O00194 | RAB27B | Ras-related protein Rab-27B | 56 | 29688 | 14.2 | 0.77 | GTPase SAR1 and related small G proteins |
| Down 62 | tr|B4DI41 | MBD1 | Methyl-CpG-binding domain protein 1 | 72 | 87409 | 1.8 | 0.80 | — |
| Down 63 | tr|B0UXB6 | ABHD16A | Abhydrolase domain-containing protein 16A | 129 | 73275 | 10.3 | 0.83 | Hydrolases of the alpha/beta superfamily |
| Down 64 | sp|Q5T8D3-2 | — | Isoform 2 of Acyl-CoA-binding domain-containing protein 5 | 148 | 64353 | 11.6 | 0.72 | Acyl-CoA-binding protein |
| Down 65 | tr|B4DNZ6 | GTF2H3 | General transcription factor IIH subunit 3 | 48 | 37020 | 4.5 | 0.79 | RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit TFB4 |
| Down 66 | sp|Q96FQ6 | S100A16 | Protein S100-A16 | 346 | 15197 | 22.3 | 0.83 | — |
| Down 67 | tr|B4DSE1 | — | cDNA FLJ55364, highly similar to CRSP complex subunit 6 | 55 | 84524 | 3.7 | 0.73 | — |
| Down 68 | tr|J3KNX9 | MYO18A | Unconventional myosin-XVIIIa | 157 | 282257 | 3.5 | 0.72 | Myosin heavy chain |
| Down 69 | tr|B4DMK6 | — | cDNA FLJ60055, highly similar to Rattus norvegicus Ssu72 RNA polymerase II CTD phosphatase homolog, mRNA | 51 | 23745 | 13.5 | 0.82 | RNA polymerase II-interacting protein involved in transcription start site selection |
| Down 70 | tr|G3V1A0 | TRAPPC4 | HCG38438, isoform CRA_b | 51 | 14838 | 20.5 | 0.81 | — |
| Down 71 | tr|B1AHA8 | HMOX1 | Heme oxygenase 1 (fragment) | 53 | 25525 | 15.5 | 0.83 | Heme oxygenase |
| Down 72 | sp|Q9Y3B3-2 | TMED7 | Isoform 2 of transmembrane emp24 domain-containing protein 7 | 193 | 24908 | 28.2 | 0.82 | — |
| Down 73 | tr|G3V1U5 | GOLT1B | Golgi transport 1 homolog B (S. cerevisiae), isoform CRA_c | 167 | 9121 | 20.3 | 0.77 | Membrane protein involved in Golgi transport |
| Down 74 | tr|B1PBA3 | — | SKNY protein | 148 | 109440 | 8.4 | 0.81 | — |
| Down 75 | sp|Q15061 | WDR43 | WD repeat-containing protein 43 | 138 | 91327 | 5.6 | 0.83 | FOG: WD40 repeat |
| Down 76 | tr|D3DUJ0 | AFG3L2 | AFG3 ATPase family gene 3-like 2 (yeast), isoform CRA_a (fragment) | 695 | 103842 | 21.2 | 0.83 | ATP-dependent Zn proteases |
| Down 77 | tr|B2RBL9 | — | cDNA, FLJ95582, highly similar to Homo sapiens breast cancer antiestrogen resistance 1 (BCAR1), mRNA | 204 | 104223 | 6 | 0.79 | — |
| Down 78 | sp|Q3SXM5-2 | — | Isoform 2 of inactive hydroxysteroid dehydrogenase-like protein 1 | 170 | 35499 | 13.5 | 0.83 | Short-chain dehydrogenases of various substrate specificities |
| Down 79 | sp|O43920 | NDUFS5 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 | 106 | 16388 | 11.3 | 0.74 | — |
| Down 80 | tr|H0YG20 | MAN1B1 | Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (fragment) | 155 | 90816 | 8.2 | 0.80 | — |
| Down 81 | tr|Q0KKI6 | — | Immunoglobulin light chain (fragment) | 66 | 28559 | 8.2 | 0.80 | — |
| Down 82 | sp|P62244 | RPS15A | 40S ribosomal protein S15a | 1521 | 18594 | 66.2 | 0.82 | Ribosomal protein S8 |
| Down 83 | tr|B4DL07 | — | cDNA FLJ53353, highly similar to ATP-binding cassette subfamily D member 3 | 398 | 92669 | 16.7 | 0.81 | ABC-type uncharacterized transport system, permease, and ATPase components |
| Down 84 | tr|B4DR67 | ALG5 | Dolichyl-phosphate beta-glucosyltransferase | 66 | 32213 | 10.9 | 0.81 | Glycosyltransferases involved in cell wall biogenesis |
| Down 85 | tr|Q9BTT5 | — | Similar to NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9 (39 kD) (fragment) | 189 | 45471 | 21 | 0.75 | Predicted nucleoside-diphosphate-sugar epimerases |
| Down 86 | tr|Q5U0H8 | — | Myelin protein zero-like 1 | 55 | 34725 | 4.8 | 0.74 | — |
| Down 87 | sp|Q5SY16 | NOL9 | Polynucleotide 5-hydroxyl-kinase NOL9 | 109 | 91782 | 7.4 | 0.79 | Predicted GTPase or GTP-binding protein |
| Down 88 | sp|O15173-2 | PGRMC2 | Isoform 2 of membrane-associated progesterone receptor component 2 | 620 | 30166 | 26.3 | 0.75 | — |
| Down 89 | sp|Q5VT52-3 | RPRD2 | Isoform 3 of regulation of nuclear pre-mRNA domain-containing protein 2 | 295 | 177879 | 4.5 | 0.82 | — |
| Down 90 | sp|Q8TC12 | RDH11 | Retinol dehydrogenase 11 | 494 | 41238 | 14.5 | 0.76 | Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) |
| Down 91 | tr|B4DZ55 | — | cDNA FLJ52097, weakly similar to Homo sapiens transmembrane and tetratricopeptide repeat containing 1 (TMTC1), mRNA | 164 | 126875 | 10.1 | 0.79 | FOG: TPR repeat |
| Down 92 | tr|J3KQA9 | MTUS2 | Microtubule-associated tumor suppressor candidate 2 | 150 | 181383 | 0.6 | 0.77 | — |
| Down 93 | sp|Q96MG7 | NDNL2 | Melanoma-associated antigen G1 | 58 | 41645 | 7.6 | 0.72 | — |
| Down 94 | tr|H3BQH3 | KLHDC4 | Kelch domain-containing protein 4 (fragment) | 107 | 47359 | 10.7 | 0.83 | — |
| Down 95 | tr|J3KN00 | NDUFA13 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 | 258 | 28599 | 23.3 | 0.81 | — |
| Down 96 | sp|Q8NF37 | LPCAT1 | Lysophosphatidylcholine acyltransferase 1 | 708 | 67346 | 15.7 | 0.82 | 1-Acyl-sn-glycerol-3-phosphate acyltransferase |
| Down 97 | sp|Q9Y5P4-2 | COL4A3BP | Isoform 2 of collagen type IV alpha-3-binding protein | 82 | 81121 | 6.7 | 0.80 | — |
| Down 98 | tr|Q5T8U5 | SURF4 | Surfeit 4 | 418 | 22863 | 39.8 | 0.81 | Predicted membrane protein |
| Down 99 | sp|P26599-2 | PTBP1 | Isoform 2 of polypyrimidine tract-binding protein 1 | 570 | 69515 | 16.2 | 0.82 | — |
| Down 100 | sp|Q8NC56 | LEMD2 | LEM domain-containing protein 2 | 137 | 63423 | 7.4 | 0.76 | — |
| Down 101 | tr|Q2Q9H2 | G6PD | Glucose-6-phosphate 1-dehydrogenase (fragment) | 2165 | 64315 | 58.3 | 0.80 | Glucose-6-phosphate 1-dehydrogenase |
| Down 102 | sp|P21796 | VDAC1 | Voltage-dependent anion-selective channel protein 1 | 2340 | 38777 | 62.9 | 0.80 | — |
| Down 103 | tr|J3KNH7 | SENP3 | Sentrin-specific protease 3 | 88 | 73986 | 7.7 | 0.78 | Protease, Ulp1 family |
| Down 104 | sp|A6NHL2-2 | TUBAL3 | Isoform 2 of tubulin alpha chain-like 3 | 768 | 51287 | 11.8 | 0.79 | Tubulin |
| Down 105 | tr|B4DR71 | — | cDNA FLJ57078, highly similar to Homo sapiens opioid receptor, sigma 1 (OPRS1), transcript variant 1, mRNA | 63 | 18151 | 8.4 | 0.83 | — |
| Down 106 | sp|Q5JRA6-2 | MIA3 | Isoform 2 of melanoma inhibitory activity protein 3 | 415 | 249369 | 7.8 | 0.80 | — |
| Down 107 | tr|J9ZVQ3 | APOE | Apolipoprotein E (fragment) | 171 | 30543 | 12.2 | 0.79 | — |
| Down 108 | tr|G5E9V5 | MRPS22 | 28S ribosomal protein S22, mitochondrial | 224 | 49264 | 17.3 | 0.77 | — |
| Down 109 | tr|B7Z7X8 | ATL2 | Atlastin-2 | 112 | 76668 | 10.8 | 0.82 | — |
| Down 110 | sp|P54709 | ATP1B3 | Sodium/potassium-transporting ATPase subunit beta-3 | 243 | 39135 | 17.9 | 0.83 | — |
| Down 111 | tr|Q6IBK3 | SCAMP2 | SCAMP2 protein | 258 | 39155 | 9.7 | 0.81 | — |
| Down 112 | tr|A4LAA3 | ATRX | Alpha thalassemia/mental retardation syndrome X-linked | 129 | 374604 | 2.5 | 0.81 | Superfamily II DNA/RNA helicases, SNF2 family |
| Down 113 | sp|Q9UK59 | DBR1 | Lariat debranching enzyme | 203 | 72182 | 14.5 | 0.80 | — |
| Down 114 | tr|B4DI61 | — | cDNA FLJ58182, highly similar to protein CYR61 | 68 | 50414 | 6.4 | 0.70 | — |
| Down 115 | tr|H3BNF1 | CLN6 | Ceroid-lipofuscinosis neuronal protein 6 | 300 | 12918 | 20 | 0.80 | — |
| Down 116 | tr|E7ERK9 | EIF2B4 | Translation initiation factor eIF-2B subunit delta | 170 | 71199 | 8.8 | 0.79 | Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family |
| Down 117 | tr|H0Y8C3 | MTCH1 | Mitochondrial carrier homolog 1 (fragment) | 97 | 50964 | 12.9 | 0.81 | — |
| Down 118 | tr|B2RMV2 | CYTSA | CYTSA protein | 52 | 149539 | 2.5 | 0.79 | Ca2+-binding actin-bundling protein fimbrin/plastin (EF-hand superfamily) |
| Down 119 | tr|I3L1P8 | SLC25A11 | Mitochondrial 2-oxoglutarate/malate carrier protein (fragment) | 470 | 37200 | 35.5 | 0.83 | — |
| Down 120 | sp|Q8NBU5-2 | ATAD1 | Isoform 2 of ATPase family AAA domain-containing protein 1 | 124 | 40468 | 11.1 | 0.72 | ATPases of the AAA+ class |
| Down 121 | sp|Q9Y3E7 | CHMP3 | Charged multivesicular body protein 3 | 102 | 32415 | 14.4 | 0.83 | Conserved protein implicated in secretion |
| Down 122 | sp|P02763 | ORM1 | Alpha-1-acid glycoprotein 1 | 262 | 28288 | 20.4 | 0.80 | — |
| Down 123 | tr|Q53F51 | — | FGF intracellular binding protein isoform b variant (fragment) | 165 | 48798 | 12 | 0.83 | — |
| Down 124 | sp|Q3ZAQ7 | VMA21 | Vacuolar ATPase assembly integral membrane protein VMA21 | 241 | 12868 | 24.8 | 0.81 | — |
| Down 125 | tr|B2R6X8 | — | cDNA, FLJ93169, highly similar to Homo sapiens GPAA1P anchor attachment protein 1 homolog (yeast) (GPAA1), mRNA | 106 | 72151 | 7.6 | 0.80 | — |
| Down 126 | sp|Q9P0S9 | TMEM14C | Transmembrane protein 14C | 45 | 12774 | 8.9 | 0.70 | — |
| Down 127 | sp|P08779 | KRT16 | Keratin, type I cytoskeletal 16 | 630 | 57054 | 23.9 | 0.62 | — |
| Down 128 | sp|Q86UT6-2 | NLRX1 | Isoform 2 of NLR family member X1 | 75 | 110309 | 4.1 | 0.71 | — |
| Down 129 | tr|Q59E99 | — | Thrombospondin 1 variant (fragment) | 153 | 155789 | 3.4 | 0.68 | — |
| Down 130 | sp|Q8WXH0-2 | SYNE2 | Isoform 2 of nesprin-2 | 149 | 986758 | 1.1 | 0.82 | Ca2+-binding actin-bundling protein fimbrin/plastin (EF-hand superfamily) |
| Down 131 | sp|P78310-2 | CXADR | Isoform 2 of coxsackievirus and adenovirus receptor | 47 | 47491 | 3.8 | 0.74 | — |
| Down 132 | tr|B2R995 | — | Malic enzyme | 98 | 77738 | 5.8 | 0.83 | Malic enzyme |
| Down 133 | tr|Q5QP56 | BCL2L1 | Bcl-2-like protein 1 (fragment) | 98 | 21810 | 23.2 | 0.82 | — |
| Down 134 | tr|H0YK72 | SEC11A | SEC11-like 1 (S. cerevisiae), isoform CRA_a | 247 | 22018 | 16.5 | 0.81 | Signal peptidase I |
| Down 135 | tr|B4DDH8 | — | cDNA FLJ55184, highly similar to Homo sapiens leukocyte receptor cluster (LRC) member 4 (LENG4), mRNA | 137 | 54865 | 8.8 | 0.79 | Predicted membrane protein |
| Down 136 | sp|Q9UJS0-2 | SLC25A13 | Isoform 2 of calcium-binding mitochondrial carrier protein Aralar2 | 719 | 86824 | 17.5 | 0.82 | — |
| Down 137 | tr|A8KAK5 | — | cDNA FLJ77399, highly similar to Homo sapiens cofactor required for Sp1 transcriptional activation, subunit 2, 150 kDa (CRSP2), mRNA | 85 | 182987 | 3.4 | 0.82 | — |
| Down 138 | tr|H0YEF3 | RNASEH2C | Ribonuclease H2 subunit C (fragment) | 76 | 18856 | 25.3 | 0.77 | — |
| Down 139 | tr|Q5QNZ2 | ATP5F1 | ATP synthase F(0) complex subunit B1, mitochondrial | 406 | 27794 | 47.7 | 0.82 | — |
| Down 140 | sp|Q6UW68 | TMEM205 | Transmembrane protein 205 | 165 | 23294 | 15.9 | 0.82 | — |
| Down 141 | tr|B3KPJ4 | PHC2 | Polyhomeotic-like protein 2 | 193 | 59764 | 9.3 | 0.79 | — |
| Down 142 | tr|H0Y4D4 | ACAA1 | 3-Ketoacyl-CoA thiolase, peroxisomal (fragment) | 131 | 30218 | 12.7 | 0.78 | Acetyl-CoA acetyltransferase |
| Down 143 | tr|Q4G0F4 | POLRMT | DNA-directed RNA polymerase | 167 | 159664 | 4.6 | 0.81 | Mitochondrial DNA-directed RNA polymerase |
| Down 144 | tr|Q6FGZ3 | EPHX1 | EPHX1 protein (fragment) | 519 | 62281 | 14.9 | 0.77 | Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) |
| Down 145 | tr|B4DVN1 | — | cDNA FLJ52214, highly similar to DnaJ homolog subfamily B member 6 | 90 | 37740 | 8.6 | 0.70 | DnaJ-class molecular chaperone with C-terminal Zn finger domain |
| Down 146 | sp|Q92667-2 | AKAP1 | A-kinase anchor protein 1, mitochondrial | 66 | 111940 | 4.9 | ||
| Down 147 | sp|O00483 | NDUFA4 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4 | 165 | 11855 | 46.9 | 0.83 | — |
| Down 148 | sp|Q9NTJ5 | SACM1L | Phosphatidylinositide phosphatase SAC1 | 179 | 77476 | 18.2 | 0.83 | Phosphoinositide polyphosphatase (Sac family) |
| Down 149 | tr|B3KVC5 | — | cDNA FLJ16380 fis, clone TLIVE2002882, weakly similar to imidazolonepropionase (EC 3.5.2.7) | 41 | 53582 | 3.3 | 0.83 | Imidazolonepropionase and related amidohydrolases |
| Down 150 | tr|B7ZLI5 | FAM98C | Family with sequence similarity 98, member C | 72 | 41696 | 9.5 | 0.68 | — |
| Down 151 | tr|B7Z6F5 | YIPF1 | Protein YIPF1 | 64 | 40866 | 2.7 | 0.61 | — |
| Down 152 | sp|Q6NVY1-2 | HIBCH | Isoform 2 of 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial | 101 | 46543 | 19.2 | 0.82 | Enoyl-CoA hydratase/carnitine racemase |
| Down 153 | tr|U3KQJ1 | POLDIP2 | Polymerase delta-interacting protein 2 | 282 | 46395 | 26.4 | 0.76 | Uncharacterized protein affecting Mg2+/Co2+ transport |
| Down 154 | tr|D6RGZ2 | THOC3 | THO complex subunit 3 | 172 | 12690 | 36.2 | 0.75 | — |
| Down 155 | tr|A0S0T0 | ATP6 | ATP synthase subunit a | 128 | 26896 | 4.4 | 0.78 | F0F1-type ATP synthase, subunit a |
| Down 156 | tr|G3V2U7 | ACYP1 | Acylphosphatase | 85 | 17520 | 14.7 | 0.80 | acylphosphatases |
| Down 157 | sp|Q9ULG6-2 | CCPG1 | Isoform 2 of cell cycle progression protein 1 | 79 | 93313 | 4.1 | 0.81 | — |
| Down 158 | tr|H7BXZ6 | RHOT1 | Mitochondrial Rho GTPase | 142 | 81600 | 5.9 | 0.77 | GTPase SAR1 and related small G proteins |
| Down 159 | sp|Q14151 | SAFB2 | Scaffold attachment factor B2 | 461 | 129824 | 13 | 0.83 | — |
| Down 160 | sp|Q96LD4 | TRIM47 | Tripartite motif-containing protein 47 | 138 | 75838 | 7.8 | 0.81 | — |
| Down 161 | tr|A8K2K2 | — | cDNA FLJ76494, highly similar to Homo sapiens GTPBP2 GTP-binding like protein 2 | 137 | 64767 | 11.7 | 0.83 | GTPase |