Table 1.
Socio-demographic and clinical characteristics for total sample and divided across disease stages
| Complete sample | Stage I | Stage II | Stage III | Stage IV | Stage V | |||
| (N = 84) | (n = 12) | (n = 22) | (n = 19) | (n = 14) | (n = 17) | |||
| Variables | Categories | Mean | Mean | Mean | Mean | Mean | Mean | p-value |
| (SD) | (SD) | (SD) | (SD) | (SD) | (SD) | |||
| Socio-demographic characteristics | ||||||||
| Age* | 56.7 (11.4) | 49.8 (9.5) | 54.6 (12.9) | 58.9 (11.1) | 61.1 (11.5) | 57.8 (9.0) | 0.084 | |
| Education (years)* | 12.9 (3.5) | 14.3 (3.3) | 13.8 (3.8) | 11.7 (3.2) | 12.5 (3.7) | 12.4 (3.3) | 0.179 | |
| n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | P-value | ||
| (2 sided) | ||||||||
| Gender | Female | 37 (44) | 5 (42) | 8 (36.4) | 7 (37) | 7 (50) | 10 (59) | 0.616 |
| Male | 47 (56) | 7 (58) | 14 (63.6) | 12 (63) | 7 (50) | 7 (41) | ||
| Education | Lower (≤12 years) | 51 (60.7) | 5 (42) | 11 (50) | 15 (79) | 9 (64.3) | 11 (65) | 0.221 |
| Higher (>12 years) | 33 (39.3) | 7 (58) | 11 (50) | 4 (21) | 5 (45.7) | 6 (35) | ||
| Marital status | Single | 36 (42.9) | 4 (33) | 7 (31.8) | 9 (47) | 8 (57.1) | 8 (47) | 0.560 |
| Married | 48 (57.1) | 8 (67) | 15 (68.2) | 10 (53) | 6 (42.9) | 9 (53) | ||
| Occupation# | Manual | 40 (47.6) | 5 (42) | 9 (40.1) | 12 (63) | 6 (46.1) | 8 (47) | 0.643 |
| Non-manual | 41 (48.8) | 7 (58) | 13 (59.1) | 7 (37) | 7 (53.8) | 7 (41) | ||
| Employment | Employed | 14 (16.7) | 11 (92) | 3 (13.6) | 0 (0) | 0 (0) | 0 (0) | <0.001 |
| Unemployed | 70 (83.3) | 1 (8) | 19 (86.4) | 19 (100) | 14 (100) | 17 (100) | ||
| Housing situation | Living at home | 52 (61.9) | 12 (100) | 22 (100) | 13 (68) | 5 (35.7) | 0 (0) | <0.001 |
| Not living at home | 32 (38.1) | 0 (0) | 0 (0) | 6 (32) | 9 (64.3) | 17 (100) | ||
| Residence | Rural | 12 (14.3) | 1 (8) | 3 (13.6) | 2 (10.5) | 3 (21.4) | 3 (18) | 0.859 |
| Urban | 72 (85.7) | 11 (92) | 19 (86.4) | 17 (89.5) | 11 (78.6) | 14 (82) | ||
| Informant | Patient Patient & | 27 (32.1) | 9 (75) | 14 (63.6) | 4 (21) | 0 (0) | 0 (0) | <0.001 |
| informant/ | 57 (67.9) | 3 (25) | 8 (36.4) | 15 (79) | 14 (100) | 17 (100) | ||
| informant only | ||||||||
| Variables | Median | Median | Median | Median | Median | Median | p-value | |
| (IQR) | (IQR) | (IQR) | (IQR) | (IQR) | (IQR) | |||
| Clinical characteristics | ||||||||
| Disease duration** | 6 (7) | 2 (2) | 5 (6) | 7 (5) | 8 (7) | 11 (7) | <0.001 | |
| Total FAS score** | 15 (17) | 24 (2) | 20 (2) | 15 (4) | 5 (3) | 0 (2) | <0.001 | |
| Independence score*** | 60 (26.5) | 95.8 (5.1) | 79.1 (2.9) | 64.7 (6.3) | 40.4 (10.8) | 20.9 (5.7) | <0.001 | |
| n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | P-value | ||
| (2-sided) | ||||||||
| Overall cognitive | Mild to moderate | 46 (54.8) | 12 (100) | 22 (100) | 12 (63.2) | 0 (0) | 0 (0) | <0.001 |
| impairment## | Severe | 34 (40,5) | 0 (0) | 0 (0) | 6 (31.6) | 12 (85.7) | 16 (94.1) | |
| Comorbid conditions | No(ne) | 48 (57.1) | 7 (58) | 9 (41) | 9 (47) | 10 (71) | 13 (76) | 143 |
| Yes | 36 (42.9) | 5 (42) | 13 (59) | 10 (53) | 4 (29) | 4 (24) | ||
FAS: Functional Assessment Scale; SD: Standard deviation; IQR: Interquartile range; *using ANOVA; **Kruskall-Wallis for k samples ***normally distributed: reported mean (sd) and Anova; all other variables Chi-square; #3 responses missing (1 in Stage IV and 2 in stage V); ##4 patients unable to evaluate (1 in Stage III, 2 in Stage IV, and 1 in Stage IV).