Table 2. Calculated PK Parameters of FruArg in Plasma.
PK parameters | |
---|---|
original concentration (C0) | 292 μM |
elimination rate (k) | 6.91 × 10–2 min–1 |
volume distribution (VD) | 2.63 × 10–3 L |
half-life (t1/2) | 10.03 min |
clearance (Cl) | 1.8 × 10–4 L·min–1 |
AUC0→last | 4.86 × 103 μM·min |
AUC0→∞ | 4.93 × 103 μM·min |