Fig. 7.

Sequential fundus autofluorescence of an RPE tear treated with aflibercept. RPE tears (a) appear as a well-demarcated central hypo-autofluorescence due to absent RPE with adjacent irregular hyper-autofluorescence corresponding to the retracted edges of RPE. The patient received anti-VEGF therapy with half-dose aflibercept. Over time (b), the lesion shows evidence of slight remodeling and resurfacing, with early centripetal recovery of autofluorescence. Note the inferior extension of the tear. Photo courtesy of Nagiel A, Sadda S, Schwartz S, Sarraf D. “Resolution of a giant pigment epithelial detachment with half-dose aflibercept.” Retinal Cases and Brief Reports. Vol 9, Issue 4, 269–272. Promotional and commercial use of the material in print, digital or mobile device format is prohibited without the permission from the publisher Wolters Kluwer Health. Please contact healthpermissions@wolterskluwer.com for further information