4-Year all-cause and cardiovascular mortality by baseline PHQ status. (A) All-cause mortality by PHQ-2 status. By 4-year follow-up, 44% of PHQ-2 (+) and 38% of PHQ-2 (−) patients had died (P=.16). (B) Cardiovascular mortality by PHQ-2 status. By 4-year follow-up, 29% of PHQ-2 (+) and 27% of PHQ-2 (−) patients had died of a cardiovascular cause (P=.44). (C) All-cause mortality by baseline PHQ-9 level among 371 PHQ-2 (+) patients. By 4-year follow-up, 44%, 50% and 37% of HF patients with PHQ-9 score levels 0–9, 10–14 and ≥15, respectively had died (P=.17). Abbreviations: PHQ-2 (+), positive Patient Health Qustionnaire-2 screen for depression; PHQ-2 (−), negative Patient Health Qustionnaire-2 screen for depression.