(b).
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| P value | OR | 95% CI | p value | |
| Sex | 0.384 | |||
| Male | 1 | Referent | ||
| Female | 1.582 | 0.788-3.175 | 0.197 | |
| Age (years), | 0.255 | |||
| PLT (×104/µL) | 0.416 | |||
| <15 | ||||
| ≥15 | ||||
| ALT (IU/L) | 0.677 | |||
| >60 | 1 | Referent | ||
| ≤60 | 0.606 | 0.286-1.281 | 0.189 | |
| AFP (ng/mL) | 0.089 | |||
| >35 | 1 | Referent | ||
| ≤35 | 1.815 | 0.935-3.525 | 0.078 | |
| Child-Pugh class | 0.115 | |||
| B/C | 1 | Referent | ||
| A | 1.797 | 0.794-4.068 | 0.160 | |
| Etiology | 0.261 | |||
| HBV | ||||
| HCV | ||||
| Imaging for surveillance | 0.755 | |||
| Combination of CT, MRI, and US | 1 | Referent | ||
| Only US | 1.004 | 0.495-2.034 | 0.991 | |
Abbreviations: OR: odds ratio, CI: confidence interval, PLT: platelet count, ALT: alanine aminotransferase, AFP: α-fetoprotein, HBV: hepatitis B virus, HCV: hepatitis C virus, CT: computed tomography, MRI: magnetic resonance imaging, US: ultrasonography