Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Oct 27;4:e2619. doi: 10.7717/peerj.2619

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

©2016 Kloetgen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.

PMC Copyright notice

(A) The PARA-suite. Dashed boxes represent software packages; all other boxes represent executable programs. The Utils package includes tools for working with error-prone sequencing data and the postprocessing package contains a tool for clustering an aligned PAR-CLIP dataset to identify RBP-bound genomic regions. (B) Read alignment by a fast read aligner is necessary to infer the error profile for a particular read dataset (we selected BWA). (C) BWA PARA is applied to the entire dataset to map error-prone reads, indicated here by the additional mapping of the two reads (shown in blue). (D) An optional alignment versus a transcriptome reference database can be executed using BWA PARA to identify previously unmapped reads.