Table 2. Binding energies between hesperetin and different types of proteins.

The energies involved in each ligand-receptor interaction was analysed using the Discovery Studio 2.5.

Proteins	Electrostatic interaction energy (kcal/mol)	Van der Waals interaction energy (kcal/mol)	Interaction energy (kcal/mol)
NsP1	16.785	−29.699	−12.914
3TRK	−454.598	−83.186	−537.784
3GPG	−405.273	−129.780	−535.053
NsP4	−32.689	−28.904	−61.594
SPK2	14.815	−27.477	−12.663