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. 2016 Oct 26;4:e2602. doi: 10.7717/peerj.2602

Table 9. Lipinski’s values of the hesperetin molecule designed for this study and that of the available data from PubChem.

A compound with drug-likeness properties should possess molecular weight less than 500 g/mol, Log P less than 5, less than 5 H-bond donors, less than 10 H-bond acceptors and molar refractivity in the range of 40–130.

Criteria From the present study Extracted from PubChem
Molecular weight (g/mol) 302.00 302.28
H-bond donors 3 3
H-bond acceptors 6 6
Log-P 2.5 2.4
Molar refractivity 76.75 76.93