Table 9. Lipinski’s values of the hesperetin molecule designed for this study and that of the available data from PubChem.
A compound with drug-likeness properties should possess molecular weight less than 500 g/mol, Log P less than 5, less than 5 H-bond donors, less than 10 H-bond acceptors and molar refractivity in the range of 40–130.
Criteria | From the present study | Extracted from PubChem |
---|---|---|
Molecular weight (g/mol) | 302.00 | 302.28 |
H-bond donors | 3 | 3 |
H-bond acceptors | 6 | 6 |
Log-P | 2.5 | 2.4 |
Molar refractivity | 76.75 | 76.93 |