Table 1.

Characteristics of person-visits from 250 HIV-uninfected men from the Multicenter AIDS Cohort Study (MACS), 1984 – 2009

Sociodemographics	Median (IQR) or %
	Overall (N = 971)
Age at blood sampling (years), median (IQR)	45.6 (39.7–52.5)
≤30	7
30.1 ≤ 40	19
40.1 ≤ 50	41
50.1 ≤ 60	24
60.1 ≤ 70	8
70.1+	1
Race
Non-black	61
Black	39
Education (at baseline)
Four-year college degree or higher	47
Less than college degree	53
Body mass index at blood sampling, kg/m2
Obese (≥30)	19
Overweight (25–29.9)	37
Normal/underweight (≤24.9)	45
Hepatitis C infection at blood sampling
Chronic	23
Cleared (Antibody+ only)	7
Negative	70
CES-D Score, mean (SD)a	11
Depressive symptomsb
Yes	29
No	72
Depressionc
Yes	37
No	63
Study site
Baltimore/Washington D.C.	22
Chicago	24
Pittsburgh	35
Los Angeles	19
Time of blood draw
A.M.	54
P.M.	47

Behaviors	Median (IQR) or % Overall (N = 971)
Smoking status at blood sampling
Current	41
Former	35
Never	24
Drinking classification at blood samplingd
Binge	11
Moderate-heavy	20
Low-moderate	50
Non drinker	19
Marijuana use since last visit
Yes	31
No	69
Amyl nitrates use since last visit
Yes	19
No	81
Stimulant use since last visite
Yes	20
No	80
Risky sex since last visitf
Yes	46
No	54
Sexually transmitted infection since last visitg
Yes	14
No	86
Morbidities (2001 – 2009)	N = 720
Persistent diabetes mellitush
Yes	9
No	91
Uncontrolled diabetesi
Yes	7
No	93
Persistent hypertensionj
Yes	49
No	51
Uncontrolled hypertensionk
Yes	30
No	70
Total cholesterol, mg/dll
Borderline-high (≥200)	34
Desirable (<200)	66
High density lipoprotein (mg/dl)	49 (40 – 58)
Low density lipoprotein (mg/dl)m	110 (88 – 137)

Abbreviations: AIDS, acquired immunodeficiency syndrome; HIV, human immunodeficiency virus; IQR, interquartile range (25%, 75%).

^aCenter for Epidemiologic Studies Depression Scale (CES-D) score 10-item version (possible range 0–30 points).

^bPresence of depressive symptoms was defined as CES-D score ≥16.

^cDepression was defined as presence of depressive symptoms (CES-D≥16) or use of depression medications.

^dBinge drinking was defined as ≥5 drinks/day for ≥ 1 month; moderate-heavy drinking was defined as 3–4 drinks/day for >1 month, or ≥5 drinks/day per month; low-moderate drinking was defined as 1–2 drinks/day or 3–4 drinks/day for ≤1 month.

^eStimulants were defined as any use of cocaine, ecstasy, methamphetamines, or any other upper.

^fRisky sex was defined as ≥2 partners [male or female] in the past six months.

^gSexually-transmitted infection was defined as any new diagnosis of herpes, syphilis, genital warts, or gonorrhea since the last visit.

^hPersistent diabetes was defined as having a history of diabetes (fasting glucose>126 mg/dL, Hemoglobin A1c≥6.5%, or use of diabetic medications) on at least 2 occasions prior to the blood sampling date.

ⁱUncontrolled diabetes was defined as fasting glucose >126 mg/dL or Hemoglobin A1c≥ 6.5% at blood sampling.

^jPersistent hypertension was defined as having a history of hypertension (systolic blood pressure ≥140 mmHg, diastolic blood pressure ≥90 mmHg, or use of anti-hypertensive medications) on at least two previous occasions from the blood sampling date.

^kUncontrolled hypertension was defined as systolic blood pressure ≥140 mmHg or diastolic blood pressure ≥90 mmHg at blood sampling.

^lSerum cholesterol measures were obtained after fasting.

^m491 person-visits had available low density lipoprotein available.