Table 2.
Proportion detectable and median (IQR) of detectable biomarker concentrations, number of person-visits (N) = 971, Multicenter AIDS Cohort Study (MACS), 1984 – 2009
| Biomarkera
| ||
|---|---|---|
| % detectable | Median (IQRb) | |
| Chemokines
| ||
| CCL11 | 100 | 1,696 (1,219 – 2,419) |
| CXCL8 | 100 | 13.3 (8.9 – 22.9) |
| CXCL10 | 100 | 139 (92 – 234) |
| CCL2 | 100 | 508 (362 – 657) |
| CCL13 | 100 | 749 (580 – 991) |
| CCL4 | 99.6 | 145 (98 – 205) |
| CCL17 | 99.9 | 531 (368 – 836) |
| CXCL13 | 98.9 | 298 (246 – 349) |
|
Cytokines | ||
| Interleukin-10 (IL-10) | 99.8 | 3.2 (2.1 – 6.3) |
| Interleukin-12p70 (IL-12p70) | 93.5 | 2.6 (1.4 – 7.4) |
| Interleukin-6 (IL-6) | 99.9 | 1.0 (0.7 – 1.5) |
| Tumor Necrosis Factor-α (TNF-α) | 99.9 | 8.5 (6.9 – 10.6) |
| B-cell Activating Factor (BAFF) | 100 | 1,970 (1,731 – 2,263) |
| Interferon-γ (IFN-γ) | 60.5 | 1.3 (0.9 – 2.1) |
| Granulocyte/Macrophage-Colony Stimulating Factor (GM-CSF) | 63.9 | 1.1 (0.7 – 2.1) |
| Interleukin-2 (IL-2) | 71.8 | 0.7 (0.5 – 1.4) |
| Interleukin-1β (IL-1β) | 55.7 | 0.5 (0.3 – 0.9) |
|
Soluble receptors | ||
| Soluble CD14 (sCD14), ng/mL | 99.9 | 2,100 (1,800 – 2,500) |
| Soluble gp130 (sgp130), ng/mL | 100 | 250 (230 – 290) |
| Soluble Interleukin 2-receptor-α (sIL2-Rα) | 100 | 1,382 (1,138 – 1,739) |
| Soluble CD27 (sCD27) | 100 | 9,067 (7,491 – 11,441) |
| Soluble TNF-receptor 2 (sTNF-R2) | 100 | 2,303 (1,867 – 2,910) |
| C-reactive protein (CRP), mg/L | 89.7 | 1.1 (0.5 – 2.4) |
a
Units are pg/mL unless otherwise indicated.
b
25th–75th percentiles.