Table 3.
Percent differences in biomarker concentrations for changes in high density and low density lipoprotein levels, Multicenter AIDS Cohort Study (MACS), 2001 – 2009
| Biomarker | High density lipoprotein levels
|
Low density lipoprotein levels
|
||
|---|---|---|---|---|
| Percent difference1 | p-value | Percent difference1 | p-value | |
| CCL11 | 0.6 | (0.809) | −1.2 | (0.611) |
| CXCL10 | −4.8 | (0.114) | −3.4 | (0.216) |
| CXCL8 | −0.9 | (0.717) | −2.0 | (0.499) |
| CCL2 | 2.4 | (0.214) | −3.1 | (0.143) |
| CCL13 | 7.3 | (0.009) | 0.5 | (0.841) |
| CCL4 | −4.2 | (0.288) | 2.9 | (0.303) |
| CXCL13 | 4.0 | (0.004) | −3.4 | (0.007) |
| IL-10 | −6.7 | (0.136) | 4.4 | (0.211) |
| IL-6 | −2.6 | (0.368) | 2.1 | (0.447) |
| IL-12p70 | 2.4 | (0.771) | −3.4 | (0.718) |
| TARC | −0.7 | (0.862) | 3.5 | (0.324) |
| TNF-α | −1.7 | (0.278) | −1.2 | (0.470) |
| IL-2 | 10.3 | (0.081) | −4.2 | (0.513) |
| IFN-γ | −10.0 | (0.074) | 3.9 | (0.588) |
| IL-1β | 2.7 | (0.763) | −14.4 | (0.167) |
| GM-CSF | 12.1 | (0.248) | −22.2 | (0.061) |
| BAFF | −1.3 | (0.266) | −0.6 | (0.588) |
| sCD14 | −1.4 | (0.448) | 0.7 | (0.649) |
| sIL-2Rα | −5.8 | (0.001) | −1.7 | (0.300) |
| sCD27 | −3.2 | (0.030) | −2.6 | (0.087) |
| sgp130 | 2.4 | (0.018) | 1.0 | (0.482) |
| sTNF-R2 | −6.4 | (0.000) | −3.0 | (0.067) |
| CRP | −15.1 | (0.010) | 20.8 | (0.002) |
1
Percent difference for a one standard deviation change in lipoprotein levels.