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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Dev Dyn. 2016 Sep 21;245(11):1081–1096. doi: 10.1002/dvdy.24438

Figure 8. Summary of proposed enteric subpopulations during zebrafish ENS development.

Figure 8

(A) At 54 and (B) 60 hpf enteric progenitors constitute a heterogeneous population of cells based on spatio-temporally dynamic expression of phox2bb, ret, and sox10. Elavl+ differentiating neurons express ret and phox2bb, but do not express sox10. (C) Proposed model for types of enteric progenitor subpopulations. Expression profiles may be indicative of a progenitor’s developmental state and its fate. Note that the phox2bb and the phox2bb/ret positive progenitor populations are likely to give rise to two different suites of neuronal subtypes.