Table 3.
Variables | Group A | Group B | Group C | Group D | Group E | F | P-value |
---|---|---|---|---|---|---|---|
dPaO2 (mmHg) | −2.20±2.04b | −5.00±4.41b | 2.00±11.70bb | 0.67±10.31bb | 9.83±9.58b | 2.207 | 0.099 |
dPaCO2 (mmHg) | −0.60±1.52b | 1.80±3.35b | 12.42±9.41b | 14.67±4.97b | −1.83±3.37b | 11.074 | 0.000 |
dPH | 0.01±0.01b | −0.02±0.02b | −0.46±0.28b | −0.40±0.13b | 0.01±0.01b | 10.07 | 0.000 |
dSaO2 | 17.14±1.33bc | 19.38±1.39b | 17.05±0.87bc | 17.76±1.47b | 16.78±1.89c | 3.652 | 0.018 |
Group A – control group without treatment; Group B – experimental COPD group without treatment; Group C – experimental COPD rats with medical oxygen exposure; Group D – experimental COPD rats with Heliox (He/O2=63%/37%) exposure; Group E – experimental COPD rats with Heliox (He/O2=71%/29%) exposure. PaO2 – arterial oxygen; PaCO2 – partial pressure of carbon dioxid; SaO2 – arterial oxygen saturation; PH – potential of hydrogen. Values are expressed as mean ±SD. Different lowercase letters (a–c) on the same line indicates significant difference (P<0.05) analyzed by one-way analysis of variance (ANOVA). Different lowercase letters (a–c) on the same line indicate significant difference (P<0.05) analyzed by one-way analysis of variance (ANOVA) followed by post hoc multiple comparisons with LSD test. P-value stands for the statistical intragroup differences according to ANOVA.