Figure 1. Schematic summary of eosinophil-tropic signaling and eosinophil cellular and humoral regulatory functions.
EOS, eosinophils; IL-5, interleukin 5; Th2, T helper cell type 2, ILC2, innate lymphoid cell type 2; Mast, mast cells; Epi, epithelium; ADCC, antibody-dependent cell-mediated cytotoxicity; Ag, antigen; PAMP: pathogen-associated molecular pattern; TLRs, toll-like receptors; DCs; dendritic cells; PMN, polymorphonuclear leukocyte (neutrophil).