Fig 3.

Subset analysis of overall survival (OS) by ipilimumab dose. Nonrandomized subset analysis of OS in patients who received ipilimumab at 3 mg/kg (n = 965), 10 mg/kg (n = 706), or other dosing regimens (n = 190) in 10 prospective trials and two retrospective, observational studies. Median OS was 11.4 months (95% CI, 10.3 to 12.5 months) for 3 mg/kg, 11.1 months (95% CI, 9.9 to 13.0 months) for 10 mg/kg, and 12.4 months (95% CI, 10.4 to 15.1 months) for other dosing regimens; the 3-year survival rates were 21% (95% CI, 17% to 24%), 24% (95% CI, 21% to 28%), and 20% (95% CI, 14% to 26%), respectively. Crosses indicate censored patients.