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Inhibition of β-catenin/CBP interaction by ICG-001 prevents MMP9 expression. (A) Untreated, ICG-001–treated, TGF-β2–treated, and TGF-β2– and ICG-001–cotreated lens explants were subjected to Western blot analysis for MMP9 and GAPDH (n = 3). (B) Graph representing the relative density ± SD of MMP9 normalized to untreated LECs (n = 3, *P < 0.02 across all samples).
