Table 5.

AUDADIS-5 and PRISM-5 concordance (ICC^a) on lifetime dimensional (severity) measures^b of DSM-5 depressive, anxiety disorders and PTSD

	Total sample				By whether participants were regular substance abusers c			By interval between interviews d
	Mean symptoms				ICC (95% CI)			ICC (95% CI)
Disorder	AUDADIS-5	PRISM-5	ICC (95% CI)	Difference in severity, signed rank test e, p-values	Regular Substance abusers	Other participants	Difference in ICCs f, substance abusers and others, p-value	Interval: at or below median (9 days)	Interval: above median (9 days)	Difference in ICCs f, those at or below the median vs. those above, p-value
Major Depression	5.8	4.0	0.60 (.51–.68)	<0.01	0.59 (.42–.71)	0.61 (.49–.70)	0.78	0.64 (.52–.73)	0.56 (.39–.68)	0.24
Persistent depression	1.3	0.9	0.64 (.56–.71)	<0.01	0.67 (.53–.77)	0.62 (.51–.71)	0.44	0.60 (.47–.69)	0.70 (.58–.78)	0.10
Specific phobia	4.2	4.2	0.81 (.77–.85)	0.87	0.78 (.69–.84)	0.84 (.79–.88)	0.11	0.80 (.73–.85)	0.83 (.77–.88)	0.40
Social anxiety	4.5	3.9	0.75 (.70–.80)	<0.01	0.75 (.65–.82)	0.76 (.68–.81)	0.83	0.75 (.67–.81)	0.76 (.67–.82)	0.83
Agoraphobia	1.3	1.2	0.77 (.72–.82)	0.08	0.78 (.70–.85)	0.76 (.69–.82)	0.65	0.80 (.73–.85)	0.74 (.64–.81)	0.17
Panic	3.3	2.8	0.76 (.70–.80)	0.03	0.74 (.64–.82)	0.76 (.69–.82)	0.68	0.75 (.68–.80)	0.76 (.67–.82)	0.83
GAD	3.9	2.1	0.19 (0.01–.35)	<0.01	0.35 (.09–.50)	0.08 (−.20–.29)	0.01	0.32 (.10–.48)	0.03 (−.33–.29)	<0.01
PTSD (20 symptoms)	9.9	8.7	0.69 (.62–.75)	<0.01	0.71 (.60–.80)	0.66 (.55–.74)	0.39	0.64 (.53–.73)	0.74 (.65–.81)	0.07
B. Intrusion symptoms (5)	2.9	2.7	0.66 (.58–.72)	0.22	0.62 (.47–.73)	0.68 (.58–.75)	0.34	0.66 (.55–.74)	0.66 (.54–.75)	1.00
C. Avoidance or efforts to avoid (2)	1.1	1.1	0.53 (.42–.62)	0.87	0.62 (.47–.73)	0.45 (.29–.58)	0.03	0.56 (.42–.67)	0.49 (.30–.63)	0.37
D. Change in cognition/mood (7)	3.4	3.0	0.63 (.54–.70)	<0.01	0.65 (.51–.75)	0.60 (.47–.69)	0.45	0.58 (.45–.68)	0.68 (.56–.77)	0.12
E. Change in arousal/activity (6)	2.5	1.9	0.62 (.53–.69)	<0.01	0.61 (.45–.72)	0.60 (.48–69)	0.89	0.50 (.34–.62)	0.74(.64–.81)	<0.01

^aICC = Intraclass correlation coefficient; CI = Confidence interval

^bDefinition of dimensional measures:

Major depression= count of major depression symptoms endorsed, from DSM-5 criterion A (maximum of 9)

Persistent depression=count of persistent depression symptoms endorsed, from DSM-5 criterion B (maximum of 6)

Specific phobia=count of specific phobia situations endorsed, from DSM-5 criterion A (maximum of 17)

Social anxiety=count of social anxiety situations endorsed, from DSM-5 criterion A (maximum of 16)

Agoraphobia=count of agoraphobia situations endorsed, from DSM-5 criterion A (maximum of 6)

Panic= count of panic disorder symptoms endorsed, from DSM-5 criterion A (maximum of 13)

GAD= count of GAD symptoms endorsed, from DSM-5 criterion C (maximum of 6)

PTSD= count of PTSD symptoms endorsed, from DSM-5 criteria B, C, D, and E (maximum of 20)

^ccurrent weekly or greater binge drinking (≥5 drinks per occasion for men, ≥4 drinks for women) or illicit drug use; depressive disorders: regular substance abusers, n=128; others, n=227; anxiety disorders and PTSD: regular substance abusers, n=136; others, n=220

^ddepressive disorders: at or below median, n=197; above median, n=158; anxiety disorders and PTSD: at or below median, n=198; above median, n=158

^eSigned rank test p-values indicate if distributions of AUDADIS-5 and PRISM-5 dimensional measures differ significantly (non-parametric equivalent of a paired t-test).

^fTest of ICCs between independent samples is from Shoukri MM: Measures of Inter-observer Agreement and Reliability, Second Edition, p. 50(Shoukri, December 2010. p.50); values <0.05 are shown in italics