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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Mucosal Immunol. 2015 Sep 9;9(2):503–514. doi: 10.1038/mi.2015.80

Figure 8. CXCL1 producing macrophages restores survival, bacterial clearance, leukocyte recruitment and cytokine production in response to K. pneumoniae infection.

Figure 8

A-B. Nlrp12−/− mice administered with WT or KO bone marrow macrophages (0.5 ×106/mouse) i.t. at the time of the infection. At 48 h post-K. pneumoniae infection, survival (A), Bacterial CFUs in the lung (B), spleen (B) and liver (B) were enumerated (n=8 mice/group). C-D. Leukocyte/neutrophil recruitment (C) and cytokine production (D) in BALF or lung homogenates was measured at 48 h post-infection (For survival, n=20 mice/group whereas for other experiments n=6-10 mice/group). *, p<0.05; **, p<0.01;***, p<0.001. Error bars represent SE.