Figure 5. Relative Risk of Developing Atrial Fibrillation after Cardiac Surgery: Sotalol versus Amiodarone The studies and data elements are organized as in Figure 2. The studies were homogeneous (I2 = 0%), thus the fixed effect model was employed for meta-analysis. The combined (weighted mean) relative risk is 1.214 (95% CI: 0.815 to 1.808) indicating no significant difference between sotalol and amiodarone in preventing atrial fibrillation following cardiac surgery (p<0.339) .