Table 2.
Serum WT1‐235 IgG levels associates with other markers
| Serum WT1‐235 IgG level | Up | Non | Sum |
|---|---|---|---|
| (A) Frequencies of WT1‐CTLs | |||
| High | 9 | 3 | 12 |
| Low | 0 | 3 | 3 |
| Sum | 9 | 6 | 15 |
| (B) DTH to WT1 peptide | |||
| Positive | 17 | 13 | 30 |
| Negative | 11 | 7 | 18 |
| Sum | 28 | 20 | 48 |
(A) p = 0.0045, (B) p = 0.0837.
Association of elevation of serum WT1‐235 IgG levels in the initial 3 months of WT1 peptide vaccine treatment and either frequencies of WT1‐specific CTLs before vaccination (A) or positive DTH to WT1‐235 peptide in the initial 3 months of WT1 peptide vaccine treatment (B) was analyzed by Spearman's correlation coefficient by rank test. Cutoff value for frequencies of WT1‐CTLs was determined as 0.16% which was mean + 2SD in 15 healthy control individuals.