Skip to main content
. 2016 Jun 8;55(31):8928–8932. doi: 10.1002/anie.201603175

Table 1.

Counterion effect under optimized reaction conditions.[a] Inline graphic

NaOTf   Yield [%][b]  
(equiv)   X=OTf X=PF6 X=BF4 X=OTs  
0   94 91 18 18  
0.5       68    
1.0   86   94 87  

[a] Reaction conditions: NaNO2 (0.16 mmol) was added to 1 (0.14 mmol) and NaOTf (0–1 equiv) in EtOAc (1 mL). The suspension was stirred at 70 °C for 16 hours. [b] Yield determined by 1H NMR analysis using 1,3,5‐trimethoxybenzene as internal standard. Tf=trifluoromethanesulfonyl.