Figure 5.

Comparison of antibody responses to 3D7a and HL1204. Antibody reactivity to purified Stage V gametocytes (above) and asexual stages (below) from both the 3D7 laboratory clone and the recently adapted polyclonal clinical isolate HL1204 (28). Study participant 080 (plasma from Visit 1) strongly recognized both gametocytes and asexual parasites from both lines. Convalescent plasma from research team member BD, a Ghanaian adult treated for symptomatic malaria at the conclusion of the fieldwork, recognized gametocytes of the Kenyan HL1204 parasites more strongly than asexual parasites of the same isolate.