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. 2016 May 23;138(1):139–149. doi: 10.1111/jnc.13382

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© 2015 The Authors. Journal of Neurochemistry published by John Wiley & Sons Ltd on behalf of International Society for Neurochemistry

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Simvastatin treatment increased lymphoid enhancer factor‐1 (LEF‐1) and T‐cell factor‐1 (TCF‐1) mRNA expression after spinal cord injury (SCI). (a) Expression levels of LEF‐1 and TCF‐1 mRNA at 3, 7, and 14 days after SCI in the three experimental groups. (b) LEF‐1 and (c) TCF‐1 mRNA expression significantly increased in the Simv‐treated animals compared with the sham and vehicle‐treated groups. GAPDH was used as a loading control. Simv, simvastatin; *p < 0.05, **p < 0.01 compared with the vehicle‐treated group. n = 4 per group.