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. 2016 Nov 1;11(11):e0165879. doi: 10.1371/journal.pone.0165879

Table 3. Annual transition probabilities used in the model (Unit: %).

Parameter Baseline Range Sources
Perinatal infection to
Immune tolerance / Inactive state 89 80–90 [15][32]
Immune tolerance / Inactive state to
Chronic hepatitis
<25 years 0.43 0.3–0.65 [11]
≥25 years 3 2.9–7.3 [11]
Chronic hepatitis to
Immune tolerance / Inactive state
<25 years 9 0–16.3 [11]
≥25 years 10 8.3–16.3 [11]
Compensated cirrhosis
<25 years 0.065 0.01–0.12 [11]
≥25 years 1.5 1–5.7 [11]
HCC 0.5 0.2–1 [15][33]
Disease-related death 0.9 0.3–3.6 [15][33]
Compensated cirrhosis to
Decompensated cirrhosis 5.4 2.8–15 [15][33]
HCC 3.3 0.5–6.6 [15][33]
Disease-related death 3.5 0–8 [13][15]
Decompensated cirrhosis to
HCC 7.1 0.15–10 [13][15][33]
Disease-related death 15 9.9–50 [15][33]
HCC to
Disease-related death 54 8.1–70 [15][33]

HCC, Hepatocellular carcinoma

HHS Vulnerability Disclosure