Table 3. Annual transition probabilities used in the model (Unit: %).
Parameter | Baseline | Range | Sources |
---|---|---|---|
Perinatal infection to | |||
Immune tolerance / Inactive state | 89 | 80–90 | [15][32] |
Immune tolerance / Inactive state to | |||
Chronic hepatitis | |||
<25 years | 0.43 | 0.3–0.65 | [11] |
≥25 years | 3 | 2.9–7.3 | [11] |
Chronic hepatitis to | |||
Immune tolerance / Inactive state | |||
<25 years | 9 | 0–16.3 | [11] |
≥25 years | 10 | 8.3–16.3 | [11] |
Compensated cirrhosis | |||
<25 years | 0.065 | 0.01–0.12 | [11] |
≥25 years | 1.5 | 1–5.7 | [11] |
HCC | 0.5 | 0.2–1 | [15][33] |
Disease-related death | 0.9 | 0.3–3.6 | [15][33] |
Compensated cirrhosis to | |||
Decompensated cirrhosis | 5.4 | 2.8–15 | [15][33] |
HCC | 3.3 | 0.5–6.6 | [15][33] |
Disease-related death | 3.5 | 0–8 | [13][15] |
Decompensated cirrhosis to | |||
HCC | 7.1 | 0.15–10 | [13][15][33] |
Disease-related death | 15 | 9.9–50 | [15][33] |
HCC to | |||
Disease-related death | 54 | 8.1–70 | [15][33] |
HCC, Hepatocellular carcinoma