Table 4. Cost estimates and disability weights used in the model.
Parameter | Baseline | Range | Sources |
---|---|---|---|
Program costs (USD) | |||
Vaccines per dose | |||
HepB birth | 0.16 | 0.14–0.186 | [34][35] |
HBIG | 23 | 14.5–31.25 | [36][37] |
HBsAg rapid test kit | 0.63 | 0.5–0.8 | [22] |
Injection supplies per dose (USD) | |||
AD syringes | 0.053 | - | [20] |
Safety boxes | 0.0064 | - | [20] |
Wastage rates (%) | |||
Vaccines | |||
HepB birth | 25 | 10–50 | [20] |
HBIG | 25 | 10–50 | Assumed |
HBsAg rapid test kit | 10 | 0–20 | Assumed |
AD syringes | 10 | 0–20 | [20] |
Safety boxes | 10 | 0–10 | [20] |
Average treatment cost (USD) | |||
Costs per morbid episode per year | 38.08 | 11.14–94.35 | [13] |
Travel and time costs | |||
Average transportation per travel (USD) | 0.31 | 0.2–0.5 | [11] |
Average time for travel/waiting/treatment at public | 2.3 | 0.96–2.76 | [11] |
health facilities (hours) | |||
Average number of outpatient visit | 1 | 0.5–2 | [11] |
Average hourly wagea (USD) | 1.23 | 1.1–1.4 | [40] |
Costs for health system strengthening (USD, million) | |||
Selective vaccination | - | 0.06–6 | [47] |
Universal vaccination | - | 0.06–6 | [47] |
Disability weights for | |||
Chronic hepatitis | 0.36 | 0.32–0.4 | [42] |
Compensated cirrhosis | 0.31 | 0.28–0.495 | [42][43] |
Decompensated cirrhosis | 0.52 | 0.12–0.92 | [42][44] |
HCC | 0.73 | 0.59–0.93 | [42][43] |
Discount rate (%) | 3 | 1.5–5 | [46] |
HepB, Hepatitis B; HBIG, Hepatitis B Immune Globulin; HBsAg, Hepatitis B surface Antigen; AD, Auto-Disable; HCC, Hepatocellular carcinoma
a. The opportunity cost of productivity loss occurs during ages from 20 years to 60 years.