Table 3. SNPs associated with MS available on the Illumina Immunochip.
| SNP identified in GWAS | Associated candidate gene | Risk allele | Odds Ratio associated with risk allele (6) |
|---|---|---|---|
| rs1315388 | HLA-DRB1*1501 | A | 3.10 |
| rs4648356 | MMEL1 | C | 1.14 |
| rs11810217 | EV15 | A | 1.15 |
| rs11581062 | VCAM1 | G | 1.12 |
| rs1335532 | CD58 | A | 1.22 |
| rs1323292 | RGS1 | A | 1.12 |
| rs7522462 | C1orf106(KIF21B) | G | 1.11 |
| rs12466022 | no gene | C | 1.11 |
| rs7595037 | PLEK | A | 1.11 |
| rs17174870 | MERTK | G | 1.11 |
| rs10201872 | SP140 | A | 1.14 |
| rs11129295 | EOMES | A | 1.11 |
| rs669607 | no gene | C | 1.13 |
| rs2028597 | CBLB | G | 1.13 |
| rs2293370 | TMEM39A/CD80 | G | 1.13 |
| rs9282641 | CD86 | G | 1.21 |
| rs2243123 | IL12A | G | 1.08 |
| rs228614 | NFKB1 | G | 1.09 |
| rs6897932 | IL7R | G | 1.11 |
| rs4613763 | PTGER4 | G | 1.20 |
| rs2546890 | IL12B | A | 1.11 |
| rs12212193 | BACH2 | G | 1.09 |
| rs802734 | THEMIS | A | 1.10 |
| rs11154801 | MYB/AHI1 | A | 1.13 |
| rs17066096 | IL22RA2 | G | 1.14 |
| rs13192841 | no gene | A | 1.10 |
| rs1738074 | TAGAP | G | 1.13 |
| rs354033 | ZNF746 | G | 1.11 |
| rs1520333 | IL7 | G | 1.10 |
| rs4410871 | MYC | G | 1.11 |
| rs2019960 | PVT1 | G | 1.12 |
| rs3118470 | IL2RA | G | 1.12 |
| rs1250550 | ZMIZ1 | A | 1.10 |
| rs7923837 | HHEX | G | 1.10 |
| rs650258 | CD6 | G | 1.12 |
| rs630923* | CXCR5 | C | 1.12 |
| rs1800693 | TNFRSF1A | G | 1.12 |
| rs10466829 | CLEC1 | A | 1.09 |
| rs12368653 | CYP27B1 | A | 1.10 |
| rs949143 | ARL6IP4 | G | 1.08 |
| rs4902647 | ZFP36L1 | G | 1.11 |
| rs2300603 | BATF | A | 1.11 |
| rs2119704 | GALC/GPR65 | C | 1.22 |
| rs2744148 | SOX8 | G | 1.12 |
| rs7200786 | CLEC16A | A | 1.15 |
| rs13333054 | IRF8 | A | 1.11 |
| rs9891119 | STAT3 | C | 1.11 |
| rs180515 | RPS6KB1 | G | 1.09 |
| rs7238078 | MALT1 | A | 1.12 |
| rs1077667 | TNFRSF14 | G | 1.16 |
| rs8112449 | TYK2/CDC37 | G | 1.08 |
| rs874628 | MPV17L2 | A | 1.11 |
| rs2303759 | DKKL1 | C | 1.11 |
| rs2425752 | CD40 | A | 1.11 |
| rs2248359 | CYP24A1 | G | 1.12 |
| rs6062314 | ZBTB46/TNFRSF6B | A | 1.16 |
| rs2283792 | MAPK1 | C | 1.10 |
| rs140522* | SCO2 | A | 1.10 |
Odds ratios taken from (6).