Schematic illustration of the preparation and application of a dual-colored QD-based ratiometric fluorescent probe for the detection of Zn2+ (A). Fluorescent images of live HCT116 cells incubated with the probe, with (B, yellow channel, C, green channel) and without Zn2+ (D, yellow channel, E, green channel). (Adapted with permission from [226]. Copyright 2015 American Chemical Society)