Figure 2.

(A) Design of a fluorescent DNAzyme immobilized onto gold nanoparticles as a selective probe of uranyl inside live cells. (B) Confocal microscopy images of HeLa cells treated with or without uranyl and incubated with active 39ES-AuNP (from left to right). (C) Schematic illustration of the design for detecting Hg²⁺ ions in a recyclable way. (D) Confocal microscopy images of MDA-MB-435 cells treated with or without 10 μM Hg²⁺ and incubated with 20 nM RBITC-PEG-AuNPs probe. (A and B: Adapted with permission from [95]. Copyright 2013 American Chemical Society, C and D: Adapted with permission from [96]. Copyright 2012 American Chemical Society)