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. 2016 Oct 27;11:5595–5610. doi: 10.2147/IJN.S104034

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© 2016 Zhao et al. This work is published and licensed by Dove Medical Press Limited

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The ROS levels in MDA-MB-231 cells treated with pGNRs@mSiO₂ or pGNRs@mSiO₂-RGD nanoprobes with or without 6 MV X-rays (6 Gy) as determined by flow cytometry.

Notes: The fluorescence intensity indicates the ROS levels. The data were quantified, and the results are presented as the mean ± SD (n=3 experiments). Compared with the pGNRs@mSiO₂-RGD + RT group, **P<0.01, *P<0.05.

Abbreviations: pGNRs@mSiO₂-RGD, RGD-conjugated mesoporous silica-encapsulated gold nanorods; ROS, reactive oxygen species; RGD, arginine-glycine-aspartic acid (Arg-Gly-Asp) peptides; MV, megavoltage; Ctr, control; RT, radiation; SD, standard deviation.