Table 1.
Radiation biology parameters of each group, which were calculated using the single-hit multi-target model
| Groups | D0 (Gy) | Dq (Gy) | SF2 | SERD0 | SERDq | SERSF2 |
|---|---|---|---|---|---|---|
| RT | 2.20 | 2.09 | 0.74 | |||
| pGNRs@mSiO2+ RT | 2.14 | 0.96 | 0.54 | 1.03 | 2.19 | 1.37 |
| pGNRs@mSiO2− RGD + RT | 1.76 | 0.84 | 0.49 | 1.25 | 2.50 | 1.52 |
Notes: pGNRs@mSiO2-RGD, RGD-conjugated mesoporous silica-encapsulated gold nanorods; pGNRs@mSiO2, mesoporous silica-encapsulated gold nanorods; RGD, arginine–glycine–aspartic acid (Arg-Gly-Asp) peptides; D0, average lethal dose; Dq, quasi-threshold dose; SF2, survival fraction at radiation dose of 2 Gy.
Abbreviations: RT, radiation; SER, sensitizer enhancement ratio.