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| Ratio | ACh | Vc1.1 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| α9 : α10 | EC50 (1) (μM) | EC50 (2) (μM) | Fraction high affinity | nH (1) | nH (2) | n | IC50 (1) (nM) | IC50 (2) (μM) | Fraction high affinity | nH (1) | nH (2) | n |
| 1:1 | 12 (4-32) | 281 (43-1700) | 0.56 (0.25-0.7) | 1 | 1 | 7 | 34 (7-44) | 11 (0.7-6.5) | 0.50 (0.37-0.63) | 1.1 (0-6) | 2.4 (0.1-3) | 5 |
| 1:3 | 22 (17-30) | nd | nd | 1 | nd | 4 | ND | 1.6 (0.87-2.8) | nd | nd | nd | 3 |
| 10:1 | 9.9 (4-21) | 537 (79-3548) | 0.60 | 1 | 1 | 4 | 34 (23-52) | 3.2 (2.2-4.4) | 0.64 (0.55-0.73) | 1.1 (0.7-1.4) | 2.1 (0.4-4.3) | 4 |
