Table 3.
Association of ADIPOQ gene variants with type 2 diabetes stratified according to body mass index
| SNPs | BMI <24 (kg/m2) | P‐value | Crude OR (95% CI) | P‐valuea | Adjusta OR (95% CI) | BMI ≥24 (kg/m) | P‐value | Crude OR (95% CI) | P‐valuea | Adjusta OR (95% CI) | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cases (n) | Control(n) | Cases (n) | Control (n) | |||||||||
| Rs3774261 | ||||||||||||
| A/A | 77 | 182 | 1 | 1 | 230 | 116 | 1 | 1 | ||||
| G/A | 161 | 294 | 0.124 | 1.294 (0.932–1.798) | 0.125 | 1.300 (0.930–1.818) | 317 | 210 | 0.059 | 0.761 (0.574–1.011) | 0.052 | 0.754 (0.567–1.003) |
| G/G | 63 | 91 | 0.021 | 1.636 (1.708–2.484) | 0.030 | 1.640 (1.407–2.457) | 145 | 73 | 0.992 | 1.002 (0.700–1.435) | 0.916 | 0.981 (0.683–1.407) |
| Rs822393 | ||||||||||||
| C/C | 73 | 125 | 1 | 1 | 199 | 119 | 1 | 1 | ||||
| C/T | 156 | 286 | 0.376 | 1.166 (0.830–1.637) | 0.543 | 1.114 (0.787–1.575) | 337 | 185 | 0.562 | 1.809 (0.816–1.455) | 0.607 | 1.080 (0.807–1.445) |
| T/T | 72 | 156 | 0.311 | 1.231 (0.824–1.839) | 0.715 | 1.080 (0.715–1.631) | 156 | 95 | 0.917 | 0.982 (0.698–1.382) | 0.804 | 0.975 (0.679–1.351) |
a
Adjusted for age and sex. BMI, body mass index; CI, confidence interval, OR, odds ratio; SNPs, single nucleotide polymorphisms.