Table 5.
Associations of the genetic variants with prediabetes‐related clinical trials among control participants
| SNP | FPG (mmol/L) | P‐value | HbA1c (%) | P‐value | HOMA‐β | P‐value | HOMA‐IR | P‐value | Systolic pressure (mmHg) | P‐value | Diastolic pressure (mmHg) | P‐value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rs3774261 | 0.438 | 0.525 | 0.150 | 0.137 | 0.066 | 0.017 | ||||||
| AA | 4.82 ± 0.31 | 5.12 ± 0.45 | 126.02 ± 96.16 | 1.64 ± 0.98 | 122.44 ± 12.26 | 80.30 ± 10.50 | ||||||
| GA | 4.85 ± 0.28 | 5.11 ± 0.49 | 127.40 ± 109.19 | 1.71 ± 0.96 | 121.06 ± 14.41 | 78.91 ± 9.14 | ||||||
| GG | 4.84 ± 0.28 | 5.15 ± 0.45 | 149.89 ± 281.49 | 1.78 ± 0.99 | 119.83 ± 14.83 | 78.23 ± 9.29 | ||||||
| Rs822393 | 0.530 | 0.043 | 0.742 | 0.848 | 0.573 | 0.263 | ||||||
| CC | 4.84 ± 0.29 | 5.12 ± 0.44 | 128.67 ± 98.58 | 1.73 ± 1.03 | 121.17 ± 13.66 | 79.24 ± 9.12 | ||||||
| CT | 4.82 ± 0.30 | 5.07 ± 0.49 | 130.93 ± 116.23 | 1.68 ± 0.96 | 121.80 ± 15.89 | 79.71 ± 9.89 | ||||||
| TT | 4.86 ± 0.27 | 5.22 ± 0.46 | 133.14 ± 241.36 | 1.71 ± 0.92 | 120.29 ± 15.69 | 79.22 ± 9.62 |
Data are presented as mean ± standard deviation. FPG, fasting plasma glucose HbA1c, glycosylated hemoglobin; HOMA‐β, homeostasis model assessment of beta‐cell function, HOMA‐IR, homeostasis model assessment of insulin resistance; SNP, single nucleotide polymorphism.