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. 2016 Nov 2;10:493. doi: 10.3389/fnins.2016.00493

Figure 7.

Figure 7

MA intake remains high in MAHDR mice under multiple intermittent MA withdrawal periods. (A) Mean (±SEM) mg/kg/18 h MA consumed for each MA concentration and group, during the MA drinking acquisition period; (B) Mean (±SEM) mg/kg/18 h MA consumed when access to 80 mg/l MA was separated by 6-, 30-, or 78-h withdrawal (abstinence) periods; (C, D) Corresponding mean (±SEM) total fluid consumed. Note: Group 1, 6 h (□) is water control group. The MA drinking group 2–4 designations are based on the variable withdrawal length after day 12. See Figure 1 for group information. ***p <0.001, compared to the next lower MA concentration; +++p <0.001, Group 2–4 compared to Group 1.