Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Oct 19;6(10):160139. doi: 10.1098/rsob.160139

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 The Authors.

Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

PMC Copyright notice

Figure 4. — Progressive docking poses of IAA (blue) and Trp (red). The residues that form the engagement niche are highlighted in violet; those that we identify later as forming a molecular filter are highlighted in orange. (a) The position of IAA at step 3 features the side-chain oriented towards the engagement niche. (b) The positions of IAA in steps 4–7 are superimposable, and show that the ring system is perpendicular to the bottom of the pocket. (c) The positions of Trp in steps 3–6 are superimposable. Its side-chain is oriented towards the niche, but the ring system is parallel, rather than perpendicular, to the pocket base. (d) At step 7, the side-chain of Trp is no longer in the niche, but points towards the pocket bottom. (e) At steps 8 and 9 (superimposable), IAA has moved towards the bottom of the pocket. (f) The positions of IAA at steps 10–15 are superimposable.